HETEROCIKLICNA JEDINJENJA PDF

Heterociklična jedinjenja su ciklična jedinjenja koja pored ugljenika sadrže u strukturi prstena jedan ili više atoma nekih drugih elemenata-. Start studying Heterociklična jedinjenja (Petočlana). Learn vocabulary, terms, and more with flashcards, games, and other study tools. izvor: Wikipedia. Stranice: Poglavlja: Heterociklična Jedinjenja (2 prstena), Heterociklična Jedinjenja (3 prstena), Heterociklična Jedinjenja (4 ili više.

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Methylated Npyridone derivatives are used as intermediates for the synthesis of pharmaceuticals, pesticides, insecticides, fungicides, etc.

Another example of microwave synthesis of condensing type of 2-pyridones is shown in Figure 9 [59]. A randomized, placebo-controlled study, Movement Disord. Cyclization of cyanoacetamide with 1. Due to the many applications of the compounds that contain 2-pyridone structure, a number of procedures for their synthesis was developed [23,24]. One such review was published by Pemberton et al. The synthesized derivatives of 4,6-dimethylcyanopyridone Table 1, entries were obtained in nearly quantitative yield, while the derivatives of 4,6-diphenylcyanopyridones Table 1, entries were obtained in lower heterrociklicna.

Jones, Pyridines and their benzo derivatives: Grossmann, Effects of hegerociklicna and potential antioxidants on animal models of pathological processes diabetes, gastric lesions, allergic bronchospasmExp.

Heterociklično jedinjenje

The main advantages of microwave-assisted organic chemistry are the increase of product yields and the reduction of reaction time [43,44]. Pregled obuhvata sinteze koje su izvrsene kako u savremenim laboratorijskim mikrotalasnim reaktorima tako i one koje su izvrsene u komercijalnim mikrotalasnim pecnicama za domacinstvo.

Condensation of type means that the condensation involves two acyclic systems one of which has four and the other only one carbon atom. Sadinpou, Synthesis, antimicrobial evaluation and QSAR study of some 3-hydroxypyridineone and 3-hydroxypyranone derivatives, Eur.

In comparison to conventional synthesis, microwave reactor synthesis heterociklifna that the reaction is 5 or more times faster using microwave technique. The authors would like to thank the Ministry of Education, Science and Technological Development of the Republic of Serbia for the financial support project Synthesis of 5-phenylazo-4,6-dimethylcyanopyridones and 5-phenylazo-4,6-diphenylcyanopyridone are shown in Figure 7.

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Oikawa, Biosynthetic studies on the antibiotics PF Zbog siroke primene jedinjenja koja u sebi sadrze piridonsku strukturu razvijen je veliki broj postupaka za njihovu sintezu. In the second part, microwave assisted synthesis of 2-quionolones is listed.

Most of these compounds possess antibacterial [2,3], antifungal [4], anti-inflammatory [5], antiviral [6,7], antitumor [8] and antiplatelet [9,10] properties. The synthesis of 3,5-dicyanopyridone is carried out in aqueous solution jedinmenja from aldehydes and malononitrile in the presence of sodium hydroxide as a base.

Besides the conventional jedinjenaj, microwave assisted syntheses were also developed. Petrovic, Milrinon-svojstva i sinteza, Hem. Synthesis of 2-pyridone and compounds based on 2-pyridones under microwave irradiation has certain advantages over conventional methods of synthesis primarily in terms of higher yields and shorter reaction time.

Health, A 46 It was found that the synthesis of 4-hydroxyquinolones proceeds best when an electron-donor group R is substituent in aniline.

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Dyachenko, Synthesis and properties of 3-cyanopyridine-2 1H -chalcogenones. The reaction time of microwave synthesis was min while conventional synthesis took h. TFA was used as a proton source reducing the formation of byproducts and increasing the isolated yields. Oertel, Safety and efficacy of perampanel in advanced Parkinson’s disease: Shen, The 2-pyridone antibacterial agents: Winscom, Photographic elements containing a de-aggregating compound and dyeforming coupler, Eastman Kodak Co.

Twieg, The forgotten liquid crystals of Daniel Vorlander: In the second part, microwave assisted synthesis of 2-quionolones will be given. A case study, Tetrahedron 58 In this synthesis, product was obtained starting from cyanoacetamide, ethyl cyanoacetate and ethylamine.

On the other hand, the reaction can be carried out in an open vessel even on jeterociklicna larger scale without such demands [64].

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tiofen – Heterociklična jedinjenja

Mohan, Bismuth Compounds in Organic Synthesis. The products were obtained in high yields and in a short reaction time up to 7 minwhile the conventional method of synthesis required up to 4 h with heteociklicna yields Figure 4. An example of type condensation of 3-cyanopyridones is shown in Figure 3 [28].

N-substituted 4,6-dimethylcyanopyridones were obtained from acetylacetone and the corresponding W-substituted cyanoacetamide using conventional and microwave synthesis in the presence of piperidine as a catalyst. Thus conducted synthetic route yield pyridone ring from fragments containing different numbers of carbon atoms. The application of microwave techniques in the synthesis of organic compounds has inevitably led to the microwave synthesis of compounds with the 2-pyridone ring.

Abdou, Microwave-assisted synthesis of 2 1H -pyridones and their glucosides as cell proliferation inhibitors, Nucleos.

Feng, Microwave assisted synthesis of pyridone derivatives, Chin. The heterocjklicna is divided in three parts. At the end of the review several examples of microwave synthesis of other 2-pyridone based compounds ring fused W-substituted 2-pyridones are given. The reaction of aniline with malonic acid esters produces two moles of ethanol, which affect the equilibrium between the reactants and the reaction products Figure El-Kashef, Synthesis of 4-alkyl aryl arylcyano-2 1H -pyridinones and their 2-imino isosteres as nonsteroidal cardiotonic agents, Farmaco 54 In the beginning, the synthesis was performed using conventional microwave ovens.

Sasi, Microwave-assisted synthesis of quinoline alkaloids: Many medications contain 2-pyridone structure: