BERLIN SDRA PDF

The ARDS Definition Task Force. Acute Respiratory Distress Syndrome: The Berlin Definition. Published online May 21, An initiative of. Endorsed by. AECC or Berlin definitions. These concerns prompted the organization of the Pediatric. Acute Lung Injury Consensus Conference (PALICC) (12). The concept . Thille AW, Esteban A, Fernández-Segoviano P, et al. Comparison of the Berlin definition for acute respiratory distress syndrome with autopsy.

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Using a consensus process, a panel of experts convened in an initiative of the European Society of Intensive Care Medicine endorsed by the American Thoracic Society and the Society of Critical Care Medicine developed the Berlin Definition, focusing on feasibility, reliability, validity, and objective evaluation of its performance.

A draft definition proposed 3 mutually exclusive categories of ARDS based on degree of hypoxemia: The draft Berlin Definition was empirically evaluated using patient-level meta-analysis of patients with ARDS from 4 multicenter clinical data sets and patients with ARDS from 3 single-center data sets containing physiologic information.

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The 4 ancillary variables did not contribute to the predictive validity of severe ARDS for mortality and sdda removed from the definition.

Compared with the AECC definition, the final Berlin Definition had better predictive validity for mortality, with an area under the receiver operating curve of bwrlin. The approach of combining consensus discussions with empirical evaluation may serve as a model to create more accurate, evidence-based, critical illness syndrome definitions and to better inform clinical care, research, and health services planning.

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Acute respiratory distress syndrome: the Berlin Definition.

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Acute Respiratory Distress Syndrome (ARDS) Definitions

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