Amphipterygium adstringens is a plant widely used in Mexican traditional medicine for its known anti-inflammatory and antiulcer properties. Amphipterygium adstringens is a deciduous shrub or small tree, commonly growing about 3 – 6 metres tall, with a broad and rather flat or sometimes narrow . PDF | Extracts from the bark of Amphipterygium adstringens, known as Cuachalalate, is in Mexico commonly used to treat several gastrointestinal disorders.

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Journal List Mediators Inflamm v.

Body weight loss and bloody stools were observed in mice acutely exposed to DSS. Intestinal anti-inflammatory activity of the Serpylli herba extract in experimental models of rodent colitis. Consistent with our results, other authors reported A.

Use of medicinal plants in Monterrey, Mexico. The pharmacological activity of medicinal plants appeared to correlate with the presence of active compounds having antioxidant and anti-inflammatory activities. Louis, MO, USA was used as positive control for bactericidal activity due to its antibacterial spectrum against Gram-positive and Gram-negative bacteria and actual application on oral hygiene; Fluconazole Pfizeran oral azole, was selected as positive control against Candida because it is frequently used in patients who suffer oropharyngeal and esophageal candidiasis.

Principles of the bark of Amphipterygium adstringens (Julianaceae) with anti-inflammatory activity.

The Dowd method [ 23 ] was used to determine the flavonoid content. However, most of these uses have an empirical basis, and in consequence, it is necessary to properly evaluate these botanical drugs to consider them as an adequate strategy to treat IBD [ 7 ].


Naringenin is another important flavonoids present in AaEE. View at Google Scholar A. Moreover, anti-inflammatory [ 15 ], hypocholesterolemic [ 16 ], antifungal [ 17 ], and antiprotozoal [ 18 ] activities have been reported as properties for this plant.

In Vitro Antimicrobial and Antiproliferative Activity of Amphipterygium adstringens

Gastroprotection and effect of the simultaneous administration of Cuachalalate Amphipterygium adstringens on the pharmacokinetics and anti-inflammatory activity of diclofenac in rats. This is, undoubtedly, a significant contribution in the field of alternative medicine towards the elaboration of novel antimicrobial agents to prevent and treat oral infections and to reduce the potential risk of systemic chronic diseases and cancer.

Abstract Amphipterygium adstringens is a plant widely used in Mexican traditional medicine for its known anti-inflammatory and antiulcer properties. It is presented by a variety of clinical manifestations, including attacks of abdominal cramps, pain, bloody diarrhea, bleed per rectum, weight loss, fever, and easy fatigability, which may begin gradually or start totally all at once [ 12 ].

Antioxidant activity and phenolic compounds in adsttringens herbs. Results were expressed as SC 50 Table 1. The Female inflorescence is in raceme about 1. Evidence-Based Complementary and Alternative Medicine.

Introduction Natural molecules and products reemerge as promising sources of complex multitarget mixtures that are used as alternative therapeutic agents for various conditions, including infections and chronic diseases [ 12 ], such as oral diseases [ 3 — 5 ] addstringens digestive cancers [ 6 ]. The sections were also stained with Alcian blue to evaluate the presence of goblet cells.


Additionally our results adstringrns novel evidence that Adstringdns. With respect to IL, this cytokine contributes to the differentiation of regulatory T cells Tregwhile suppressing dendritic cell-associated Th1 and Th17 immunity, as well as regulating inflammatory responses [ 3637 ]. From Wikipedia, the free encyclopedia. Experimental colitis models have been used to identify therapeutic agents and elucidate the underlying physiologic mechanisms of UC.

Amphipterygium adstringens

These results are consistent with previous work demonstrating higher sensitivity of S. Adstriingens plant and bark of Amphipterygium adstringens growing in Michoacan, Mexico. This observation suggests that A. In another study, naringenin ameliorated DSS-induced colitis by restoring the expression of tight junction proteins such as occludin, junctional adhesion molecule-A, and claudin-3 [ 46 ].

The most sensitive strain was S. Its leave arrangements is imparipinnate with petioles that average 5. View at Google Scholar R. These phytochemicals compounds of AaEE have been found to induce a wide spectrum of activities such as reduction asdtringens oxidative stress, suppression of inflammation, and cell proliferation and modulating numerous signal transduction pathways.

Medicinal plant-based traditional medicine has long provided ethnopharmacotherapy for the treatment of chronic inflammatory disorders. The extract of the A.

These leaflets have a cuneate base and an obtuse adstringejs rounded apex, its margin is dentate or crenate.

The male flower is actinomorphic.